[The three-monthly paliperidone palmitate depot in the treatment of schizophrenia].

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[The three-monthly paliperidone palmitate depot in the treatment of schizophrenia].

Tijdschr Psychiatr. 2018;60(12):827-833

Authors: Spoelstra SK, Bais L, Knegtering H

Abstract
BACKGROUND: A three-monthly formulation of intramuscular paliperidone palmitate has been available on the Dutch and Belgian markets since 2016.<br/> AIM: To provide an overview of the indication, effectiveness and side-effects of this injectable three-monthly formulation of paliperidone and to offer considerations for clinical practice.<br/> METHOD: A clinically-oriented literature study.<br/> RESULTS: Three-monthly paliperidone palmitate depot appears to be as effective as the monthly paliperidone depot and has the same profile of side-effects. <br/> CONCLUSION: Three-monthly paliperidone palmitate is an effective treatment option for schizophrenia. However, future research and clinical practice need to clarify the position of this depot in the treatment trajectory.

PMID: 30536295 [PubMed - in process]