Combined typical and atypical long-acting injectable antipsychotics in treatment-resistant schizophrenia: two case reports.

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Combined typical and atypical long-acting injectable antipsychotics in treatment-resistant schizophrenia: two case reports.

Psychiatry Clin Neurosci. 2018 Nov 25;:

Authors: Li FL, Yeh TC, Yang FC, Liang CS

Abstract
Real-world data have shown that clozapine and long-acting injectable (LAI) antipsychotics (LAIAs) were more effective than oral antipsychotics in preventing relapse in schizophrenia.1 A treatment dilemma emerges when managing patients with treatment-resistant schizophrenia (TRS) refusing oral antipsychotics, as the treatment of choice, LAI clozapine, is not available. We reported on two patients with TRS successfully managed with combined typical and atypical LAIAs. Informed consents have been obtained from both patients' family. This article is protected by copyright. All rights reserved.

PMID: 30474344 [PubMed - as supplied by publisher]

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