Persistence in treatment for one year among patients in Nigeria with first-episode schizophrenia.

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Persistence in treatment for one year among patients in Nigeria with first-episode schizophrenia.

Psychiatr Serv. 2014 Sep 1;65(9):1174-6

Authors: Esan O

Abstract
OBJECTIVE: The aim of this study was to examine the magnitude of poor persistence in treatment among patients with schizophrenia and to identify associated factors.
METHODS: All eligible patients (N=216) seen at the University College Hospital in Ibadan, Nigeria, over a five-year period were retrospectively followed up until the time of their last visit. Time to first default was examined by Kaplan-Meier survival analyses. A log-rank test was used to compare survival times for different variables. The contribution of the variables that affected time to default was examined by Cox regression analysis.
RESULTS: Only 24% of the sample remained in treatment at the one-year follow-up. Persistence as measured by mean±SE time to all-cause treatment default was 17.80±1.44 weeks. Of several variables examined, including whether patients were taking first- or second-generation antipsychotics, none were found to predict persistence.
CONCLUSIONS: Persistence in treatment of patients with a first episode of schizophrenia was low.

PMID: 25179189 [PubMed - indexed for MEDLINE]

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