Atypical psychotic symptoms and Dandy-Walker variant.

Atypical psychotic symptoms and Dandy-Walker variant.

Neurocase. 2016 Sep 23;:1-4

Authors: Williams AJ, Wang Z, Taylor SF

New-onset psychotic symptoms often respond well to antipsychotic treatment; however, symptoms may be difficult to treat when an underlying brain malformation is present. Here, we present a case of atypical psychotic symptoms in the context of a congenital cerebellar malformation (Dandy-Walker variant). The patient ultimately improved with paliperidone palmitate after multiple antipsychotic medication trials (both oral and one long-acting injectable) were ineffective. Neuroimaging may provide valuable diagnostic and prognostic information in cases of new-onset psychosis with atypical features and treatment resistance, even in the absence of neurologic signs and symptoms.

PMID: 27662527 [PubMed - as supplied by publisher]

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